Metabolomics: Developing and optimizing a robust HRAM GC-MS pipeline for on-breath global biomarker analysis

WHITE PAPER 10727 Breath Biopsy with TD-GC-Orbitrap: a non-invasive approach for disease detection Authors: Dominic Roberts1, Cristian Cojocariu1, Kayleigh Arthur2, Jonathan Lawson2; 1Thermo Fisher Scientific, Runcorn, UK; 2Owlstone Medical, Cambridge, UK Keywords: Breath Biopsy, early detection, respiratory disease, biomarkers, Thermal…

Breath Biopsy: combining Thermal Desorption-Gas Chromatography with High Resolution Mass Spectrometry for improved sensitivity and selectivity in untargeted breath analysis Lori Dolata1, Dominic Roberts1, Cristian Cojocariu1, Paul Silcock1, Jason Cole1, Max Allsworth2. 1Thermo Fisher Scientific, Runcorn, UK. 2Owlstone Medical Ltd.,…

Large-scale targeted biomarker analysis of volatile organic compounds in breath by TD-GC-MS Darren Barrington-Light, Thermo Fisher Scientific, Altrincham, United Kingdom Mircea Martiniuc, Owlstone Medical Ltd, Cambridge, United Kingdom; Laercio Pires Fernandes Jr, Thermo Fisher Scientific, Altrincham, United Kingdom View Settings…

White paper | 003116 GC-MS Grant application resource: Using the Orbitrap Exploris GC 240 mass spectrometer to accelerate research Keywords Orbitrap Exploris GC 240 mass spectrometer, Orbitrap technology, accurate mass, complex matrices, high resolution, screening, gas chromatography, unknown identification, structural…