AdvanceBio Peptide Mapping - An HPLC Column Technology for Faster Protein Biocharacterizations

Fast and Efficient Peptide Mapping of a Monoclonal Antibody (mAb): UHPLC Performance with Superficially Porous Particles Application Note Biotherapeutics and Biosimilars Authors Introduction James Martosella, Alex Zhu Peptide mapping by reversed-phase (RP) chromatography is the mainstay technique in biotherapeutic analysis,…

Reversed-Phase for Biomolecules: From Column Selection to Troubleshooting Melissa Goodlad, PhD Columns and Supplies Applications Engineer October 5, 2023 Agenda • Introduction to reversed-phase chromatography • Column selection • Protein separations • Peptide separations • Oligonucleotide separations 2 October 5,…

Agilent-NISTmAb Peptide Mapping Agilent BioHPLC Columns Application Compendium Contents Agilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted from NISTmAb RM 8671 batch. Quality control (QC) testing is performed using Agilent LC-MS system. QC batch release test includes aggregate profile, charge variants…

High-Resolution Mapping of Drug Conjugated Peptides in an ADC Digest Peptide map comparison of mAb and drug conjugated mAb Application Note Biologics and Biosimilars Author Introduction Suresh Babu C.V. Currently, antibody drug conjugates (ADCs) are prime protein drugs for biotherapeutic…