High-Resolution Mapping of Drug Conjugated Peptides in an ADC Digest

Analysis of Tryptic Digests of a Monoclonal Antibody and an Antibody-Drug Conjugate with the Agilent 1290 Infinity II LC Application Note Biopharmaceuticals and Biosimilars Authors Abstract Gerd Vanhoenacker, Mieke Steenbeke, An Agilent 1290 Infinity II LC in combination with an…

Agilent BioHPLC columns Characterization of Antibody-Drug Conjugate Critical Quality Attributes Application compendium Contents Introduction3 Featured application notes 2 PLRP-S Polymeric Reversed-Phase Column for LC/MS Separation of mAbs and ADC (5991-7163EN) 5 Intact- and Peptide-Level Characterization of Trastuzumab Emtansine In Vitro…

Application Note Biopharma Identification of Conjugation Sites in an Antibody Drug Conjugate Using the Agilent 6545XT AdvanceBio LC/Q-TOF system Author Abstract Yulan Bian Agilent Technologies, Inc. This application note highlights the workflow of drug conjugation site identification in an antibody…

Agilent Biocolumns Critical Quality Attributes Application Compendium Contents Introduction 05 1 Titer determination 07 1.1 1.2 1.3 1.4 1.5 Background Getting Started How to Guide - Affinity Chromatography for Titer Determination Featured Application Notes Cell Clone Selection Using the Agilent…