Fitting of ETD Rate Constants for Doubly and Triply Charged Ions in a Linear Ion Trap

APPLICATION NOTE 74160 Proton transfer charge reduction (PTCR) improves spectral matching and sequence coverage in middle-down analysis of monoclonal antibodies Luca Fornelli,1 Ryan N. Oates,1 Kristina Srzentić,2 Christopher Mullen,3 John E. P. Syka,3 and Romain Huguet3 University of Oklahoma, Norman,…

Middle-down Analysis of Monoclonal Antibody Middle using Nano-flow Liquid Chromatography and a Novel Tribrid Orbitrap Mass Spectrometer Jie Qian,1 Keith A. Waddell, 2 Zhiqi Hao2 1 Thermo Fisher Scientific, Somerset, NJ, 2Thermo Fisher Scientific San Jose, CA Overview Results Purpose:…

ThP 474 ( ) MS imaging i gi g enabling bli g visualization i li ti off lipid lipid C=C C Cp positional iti l iisomers iin bi biological l gi l ti tissues using i g Oxygen O yg…

Profiling the Serine Hydrolase Superfamily using Activity-based Probes Ryan D. Bomgarden1, Rosa I. Viner2, Chris L. Etienne1, John C. Rogers1 1Thermo Fisher Scientific, Rockford, IL; 2Thermo Fisher Scientific, San Jose, CA Overview Results Purpose: Profiling serine hydrolase expression and activity…