Proton transfer charge reduction (PTCR)

65653 WHITE PAPER Go beyond in biopharmaceutical characterization Unprecedented insights into the most advanced biotherapeutics are revealed by utilizing the pioneering technology and software developments incorporated into the Thermo Scientific™ Orbitrap Eclipse™ Tribrid™ mass spectrometer. Abstract The pioneering technology and…

Technical note | 003318 Biopharma In-depth characterization of monoclonal antibodies Intact mass analysis and middle-down mass spectrometry approaches on an Orbitrap Ascend BioPharma Tribrid mass spectrometer Authors Goal Jingjing Huang, Christopher Mullen, To assess the performance of the Thermo Scientific™…

WHITE PAPER 65971 Grant application resource Go beyond today’s discovery with the Orbitrap Eclipse Tribrid mass spectrometer Keywords: Orbitrap Eclipse Tribrid Mass Spectrometer, FAIMS Pro Interface, Mass Spectrometry, Quantitative Proteomics, TMT and TMTpro Multiplexing, Single-cell Sensitivity, Top-down Proteomics, Native Intact…

Improved Middle-Down Characterization of Antibodies Using Multiple Ion Activation Techniques and Ion-Ion Proton Transfer Reactions on a Modified Orbitrap Mass Spectrometer John E.P. Syka, Christopher Mullen, Stephane Houel, Romain Huguet, Joshua A. Silveira, Helene L. Cardasis, and Vlad Zabrouskov; Thermo…