A pre-concentration and online solid phase extraction setup for the LC-MS analysis of therapeutic protein mixtures

Technical note | 001259 Native mass spectrometry Rapid online buffer exchange Solutions for high-throughput analysis of large biomolecules by native mass spectrometry Authors Why do we need rapid online buffer exchange? Weijing Liu , Samy Memmi , Terry Zhang ,…

Application note | 001391 Biopharma Improved and universal inline electrochemical reduction and subunits LC-MS analysis of multiple classes of monoclonal antibodies Authors Application benefits Sara Carillo, Tomos E. Morgan, Hendrik1 1 • Reduced mAb and reduced subunits analysis can be…

TECHNICAL NOTE 72203 Tandem UHPLC operation for high-throughput LC-MS peptide mapping analyses Authors Martin Samonig, Sabrina Patzelt, Carsten Paul, Martin Rühl, and Remco Swart Thermo Fisher Scientific, Germering, Germany Keywords Dual column, dual gradient, offline reconditioning, alternating column regeneration, Vanquish…

Martin Samonig, Remco Swart Thermo Fisher Scientific, Germering, Germany Appli cat i on N ote 1 1 3 3 SEC-MS with Volatile Buffers for Characterization of Biopharmaceuticals Key Words Monoclonal Antibodies, MAbPac SEC-1, Biocompatible UHPLC, Biotherapeutics Characterization, Biopharma Goal Prove…