A Single Analytical Platform for Glycan Analysis, Charge Heterogeneity, and Purity Determination of the NISTmAb

Capillar y electrophoresis k its Kits to meet the challenges of today with the flexibility for tomorrow The Power of Precision Quantify size and purity, either reduced or non-reduced 390953 SDS-MW Analysis Kit / A10663 IgG Purit y /Heterogeneit y…

Charge Heterogeneity Analysis of Intact Infliximab Using CESI-MS and Neutral OptiMS Cartridge Fang Wang1, Tingting Li1, Esme Candish2 1 SCIEX, Brea, CA; 2SCIEX, Framingham, MA; Key Features • Capillary zone electrophoresis (CZE) separation and Mass spectrometric (MS) identification of charge…

Subunit charge variant characterization in the native state Fang Wang1 Zoe Zhang2, 1SCIEX Brea, CA (USA) 2 SCIEX Redwood City, CA (USA), Monoclonal antibody (mAb) therapeutics often contain charge variants that arise from a wide array of post-translational modifications (PTM),…

Agilent BioHPLC Columns Characterization of NIST Monoclonal Antibody Critical Quality Attributes Application Compendium Contents Agilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted from NISTmAb RM 8671 batch. Quality control (QC) testing is performed using Agilent LC-MS system. QC batch release test…