RNA Analysis for CRISPR by capillary electrophoresis with laser-induced fluorescence detection

Gene Therapy and Oligonucleotide Compendium Volume 1 Gene Therapy and Oligonucleotide Compendium Contents Introduction 4 Growing trends and emerging technologies for oligonucleotide and gene therapies 6 The global gene therapy & oligonucleotide market 8 Regional landscape North America EMEAI (Europe,…

Application Note CRISPR Single Guide RNA Characterization by IP- RP-LC-MS with a Premier Oligonucleotide BEH 300 Å C18 Column Maissa M. Gaye, Chris Knowles, Balasubrahmanyam Addepalli, Matthew A. Lauber Waters Corporation Abstract The high speed, low cost, and reduced need…

Genome Sizing Methodology for Genome Integrity Analysis of Adeno-Associated Viruses (AAV) Jane Luo, Tingting Li, Fang Wang, Sahana Mollah, Handy Yowanto SCIEX, Brea, California Introduction Adeno-associated virus (AAV) is a small (25-nm) virus that is composed of a non-enveloped icosahedral…

Application Note Biopharma From Narrow to Ultrawide Pores: Characterization of mAbs, AAVs, mRNA, and pDNA Using size-exclusion chromatography Authors Jelle De Vos, Silke D'Haeyer, Pat Sandra, and Koen Sandra RIC group President Kennedypark 6, 8500 Kortrijk, Belgium Anne Blackwell and…