Effective Monitoring for Enantiomeric Forms of Methamphetamine and Related Compounds by LC/MS

Application Note Clinical Research Chiral separation of methamphetamine and amphetamine on an Agilent InfinityLab Poroshell 120 Chiral-V column with detection by LC/MS Authors Abstract Carl Griffin and William Long Agilent Technologies, Inc. Wilmington, DE, USA An Agilent InfinityLab Poroshell 120…

A Novel Approach in HPLC Chiral Method Development: Dealing with Multiple Chiral Centers David S. Bell1, Anders Fridstrom2, and Gaurang Parmar1 1Supelco, Div. of Sigma-Aldrich Bellefonte, PA 16823 USA 2Sigma-Aldrich GmbH Industriestrasse 25 CH-9471 Buchs, Switzerland sigma-aldrich.com/analytical T413140 © 2013…

Basics of Chiral HPLC Definitions Principles Available CSPs Mobile phase types T408109 sigma-aldrich.com The Field of Stereochemistry 1. All isomers have same chemical formula but differ in the arrangement of certain chemical groups in space. 2. Many types of isomers…

Application Note Pharma & Biopharma Quantitation of the Chiral Shift in Metabolism of Propranolol Using 2D-LC/MS/MS The Agilent InfinityLab 2D-LC Solutions for achiral‑chiral analysis of complex samples Authors Lukas C. Harps, Felix Bredendiek, and Maria K. Parr Freie Universitaet Berlin…