Sensitive profiling of IgG1 monoclonal antibody variants under native conditions

Analytical solutions for biopharmaceutical characterization and control Your partner on every step of your journey Together we can address the challenges of biotherapeutic drug development Your molecules are complex Biotherapeutics such as monoclonal antibodies, biosimilars, antibody-drug conjugates, and nucleotide-based therapies…

Biopharma Protein solutions eBook Protein therapeutics: At a glance Protein therapeutics are a type of biotherapeutics derived from genetically engineered human proteins. They offer several advantages over small-molecule drugs, allowing for more precise targeting of complex functions. Compared to chemical…

Application note | 004167 Biopharma Charge variant analysis of cysteine-linked antibody-drug conjugates using an online multiple heart-cut 2DSCX-SEC-LC HRAM MS approach Authors Application benefits Xuepu Li¹, Xiaoxi Zhang¹, Maria Grübner², • The online multiple heart-cut two-dimensional liquid chromatography (2D-LC) system…

Chromatographic Workflows for Biopharmaceutical Characterization Dr. Ken Cook European Bioseparation Sales Support Expert Thermo Fisher Scientific, Hemel Hempstead/Germany The world leader in serving science Fulfilling the Needs of Biotherapeutic Characterization Charge variant screening Peptide mapping Released glycan analysis Aggregate screening…