SCIEX CZE Rapid Charge Variant Analysis Kit

Native State Charge Variant Analysis of Commercialized Monoclonal Antibodies in Minutes CZE Rapid Charge Variant Analysis Kit Peter Holper, SCIEX Redwood City, CA Introduction A As biopharmaceutical companies face increasing pressure to decrease the overall drug development timeline, analytical researchers…

Capillar y electrophoresis k its Kits to meet the challenges of today with the flexibility for tomorrow The Power of Precision Quantify size and purity, either reduced or non-reduced 390953 SDS-MW Analysis Kit / A10663 IgG Purit y /Heterogeneit y…

Subunit charge variant characterization in the native state Fang Wang1 Zoe Zhang2, 1SCIEX Brea, CA (USA) 2 SCIEX Redwood City, CA (USA), Monoclonal antibody (mAb) therapeutics often contain charge variants that arise from a wide array of post-translational modifications (PTM),…

Charge Heterogeneity Analysis of Intact Infliximab Using CESI-MS and Neutral OptiMS Cartridge Fang Wang1, Tingting Li1, Esme Candish2 1 SCIEX, Brea, CA; 2SCIEX, Framingham, MA; Key Features • Capillary zone electrophoresis (CZE) separation and Mass spectrometric (MS) identification of charge…