2019/2021 Chromatography Consumables Catalog

Significance of the topic

The quality and reproducibility of chromatographic analysis depend on every element of the sample-to-knowledge workflow. From sample preparation to the final detection, suboptimal consumables can compromise sample integrity, reduce instrument uptime and drive up costs due to reanalysis. Integrated chromatography solutions—featuring coordinated consumables, columns and vials—help laboratories in biopharma, pharmaceutical, food & beverage, environmental and clinical sectors maintain high productivity and data confidence while minimizing failures and wasted resources.

Objectives and overview of the catalogue

Thermo Fisher Scientific’s Chromatography Consumables Catalog presents a unified portfolio of products designed to optimize connected workflows. The catalogue aims to:

• Familiarize users with a range of sample preparation technologies (manual and automated), cartridges, plates and columns
• Highlight compatible vials, closures and autosampler accessories that ensure leak-free operation and minimal evaporation
• Showcase column chemistries and formats for HPLC/UHPLC, GC and specialty separations
• Provide guidance for product selection across key applications and industries

Methodology and instrumentation

Product development emphasizes performance validation and batch-to-batch consistency. Key methodologies include the testing of frit-less SPE formats (SOLA, HyperSep), supported liquid extractions (HyperSep SLE) and rapid protein digests (SMART Digest). Extensive compatibility testing ensures seamless integration with major liquid-handling platforms and autosamplers. Notable instrumentation highlighted includes Thermo Scientific Vanquish UHPLC, Q Exactive mass spectrometers, KingFisher liquid handlers and TriPlus HS systems for headspace analysis.

Main results and discussion

Validation data demonstrate:

• Up to 20× sensitivity gains by loading larger volumes on SPE devices and eluting into minimal volumes
• Consistent retention times with relative standard deviations below 0.03 % for peptide digests
• Rapid protein digestion protocols (as little as 60 min versus traditional 12–16 h) with high sequence coverage
• Uniform low particulate counts in MS-certified vials, eliminating background interferences

Benefits and practical applications of the methods

These connected consumables and workflows deliver tangible advantages for analytical laboratories:

• Reduced sample handling errors and re-injections through robust closure systems (AVCS, SureStop)
• Faster throughput with automated SPE, SLE and on-line trapping columns
• Broad application coverage from small molecules to biologics, pesticides to environmental pollutants
• Ease of method scaling for limited sample volumes and high-throughput demands

Future trends and possibilities

Continued integration with digital selection tools and cloud-based method libraries will drive smarter consumable choices. Automation platforms will increasingly leverage AI-driven protocols for SPE and sample preparation. Emerging chemistries and microfabricated devices will further miniaturize workflows and enable trace-level analyses in limited-volume matrices. Sustainable materials and reduced solvent requirements will also shape next-generation consumables.

Conclusion

Thermo Fisher Scientific’s connected chromatography consumables catalog showcases an end-to-end portfolio that supports reproducible, efficient and sensitive analyses across diverse fields. By selecting the right combination of sample preparation devices, vials, closures and columns, laboratories can achieve maximum instrument uptime, data integrity and operational efficiency.