Sample Preparation, Consumables
IndustriesEnvironmental, Food & Agriculture, Pharma & Biopharma, Clinical Research
ManufacturerThermo Fisher Scientific
Significance of Connected Chromatography Consumables
High-sensitivity applications and high-throughput laboratories depend on reliable, tightly integrated workflows that span sample preparation to final detection. Consistent sample integrity, minimal evaporation, and low background contamination are critical to reproducible results and cost-effective operations.
Objectives and Overview
Provide a unified portfolio of chromatography consumables designed to optimize every stage of the analytical workflow:
- Sample preparation cartridges and plates
- Autosampler vials, plates and closures
- Column chemistries for LC and GC
- Tools and accessories for vial capping and decapping
Methodology and Instrumentation
Major components and compatible instrumentation:
- Sample handling: manual and automated SPE, SLE and protein digestion kits
- Autosampler vials and plates: AVCS closures, SureStop vials, Chromacol GOLD vials, WebSeal plates
- Columns: UHPLC and HPLC chemistries (C18, biphenyl, HILIC, SEC, WCX, HIC, glycan, GC phases)
- Autosamplers and systems: Thermo Fisher Vanquish, TriPlus HS, AS 3000, TriPlus RSH, PAL/CTC/LEAP, Gerstel
- Tools: electronic and manual crimpers/decrimpers for 8, 9, 11, 13 and 20 mm caps
Main Products and Discussion
Key product lines and design features:
- AVCS closures with SureStop vials deliver crimp-equivalent seals without tools and eliminate septum push-through
- Chromacol GOLD vials use low-alkali glass for minimal adsorption of trace analytes
- MS Certified vials are pre-cleaned and tested for sub-micron particulates to support sensitive LC-MS and GC-MS assays
- National™ brand offers broad compatibility with most autosamplers, including economy and certified options
- WebSeal well plates and mats for LC-MS and GC workflows, available in multiple formats (96/384, U-, V- and deep well)
Benefits and Practical Applications
Consumables deliver:
- Improved data integrity through consistent sealing and low background levels
- Reduced sample loss, carryover and reanalysis by using optimized insert and vial designs
- Higher lab productivity via tool-free capping, color-coded vials and barcoded plates for automated systems
- Enhanced method sensitivity supported by inert glass and low-particle, pre-cleaned surfaces
Future Trends and Possibilities
Emerging directions include:
- Digital integration of workflows via cloud-based method repositories (AppsLab) and instrument software
- Greater automation with robotic sampling, electronic crimping and barcoded consumables
- Miniaturization to lower solvent use and improve sustainability
- New coatings and materials for even lower sample binding and wider chemical compatibility
Conclusion
The connected consumables portfolio empowers laboratories to achieve reproducible, high-throughput chromatography across diverse applications, while reducing costs and ensuring sample integrity.
Reference
- No external literature cited.
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