Application Note Advancing Analysis of Covalent High Molecular Weight Insulin With ACQUITY® Premier SEC 125 Å Columns Philip Wuthrich, Stephan M. Koza, Steve Shiner Waters Corporation Abstract Here we perform denaturing SEC analysis of human insulin with an ACQUITY Premier…
[ CARE AND USE MANUAL ] XBridge Premier Protein SEC 250 Å, 2.5 µm Columns CONTENTS I. INTRODUCTION Thank you for choosing a Waters™ SEC Column. The XBridge™ I. INTRODUCTION II. SEC ANALYSIS OF PROTEIN AGGREGATES, MONOMERS, AND FRAGMENTS…
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Application Note Rapid Size Variant Analysis of Monoclonal Antibodies Using UPLC™ and HPLC Compatible MaxPeak™ Premier Protein SEC Columns Stephan M. Koza, Ying Qing Yu Waters Corporation Abstract High-throughput and rapid size-exclusion chromatography (SEC) methods can be useful to support…
Application Note MaxPeak Premier Protein SEC 250 Å Column Lifetimes at Physiological pH for Polysorbate (Tween) Formulated Biosimilar Monoclonal Antibodies Stephan M. Koza, Hua Yang, Ying Qing Yu Waters Corporation Abstract Self-associated or aggregated protein impurities in therapeutics is a…
