Advanced SEC with Online LS/DLS Detection for the Analysis of Lipid Nanoparticles CQAs

Enhance Biopharma Insights with Advanced Size Exclusion Chromatography Agilent Biopharma SEC Solutions 2 3 Size exclusion chromatography (SEC) plays an essential role in the analysis of biopharmaceutical modalities like monoclonal antibodies, viral vectors, mRNA, and other. SEC enables the determination…

Application Note Biopharma Analysis of mRNA-Lipid Nanoparticles in Human Plasma using SEC-Static Dual-Angle Light Scattering and Refractive Index Detection Authors Introduction Brian Liau, Suresh Babu C.V., and Ravindra Gudihal Agilent Technologies, Inc. In recent years, lipid nanoparticles have been used…

mRNA/LNP Multiattribute Quantitation of Payload(s), Size and Heterogeneity With Size Exclusion Chromatography Coupled to Multiangle Light Scattering a b b a Mateusz Imiołek , Lavelay Kizekai , Bala Addepalli , Szabolcs Fekete , Matthew Lauber a - Waters Corporation, Rue…

Characterizing Vaccines with the Light Scattering Toolkit Biophysical analysis aids in discovery, development and production 1 Table of Contents Introduction 3 Chapter 1: The light scattering toolkit 5 Multi-angle light scattering: Molar mass, radius and beyond 6 Dynamic Light Scattering:…