Characterization of polysorbate 80 in (bio)pharmaceuticals using HPLC-CAD

Pharma and biopharma Characterization of polysorbate 80 in (bio)pharmaceuticals using HPLC with charged aerosol detection Sylvia Grosse, Katherine Lovejoy Thermo Fisher Scientific, Germering, Germany Abstract Materials and methods Purpose: This work demonstrates the characterization of a polysorbate 80 (PS80) formulation…

APPLICATION NOTE 73979 Polysorbate 80 profiling by HPLC with mass and charged aerosol detection Authors: Mauro De Pra, Denis A. Ispan, Katherine Lovejoy, Sylvia Grosse, Stephan Meding, Frank Steiner Thermo Fisher Scientific, Germering, Germany Keywords: Vanquish Flex, Vanquish Duo, ISQ…

Simultaneous analysis of polysorbate 80 and poloxamer 188 in biopharmaceutical formulations using charged aerosol detector and single quadrupole mass spectrometer Xuepu Li 1, Sissi White 2, Mauro De Pra 3, Yu Cui 1, Min Du 2 1Thermo Fisher Scientific, Shanghai,…

Combining mass spectra, retention time modelling, and charged aerosol detection for unambiguous peak annotation and uniform-response quantitation in polysorbate profiling Denis A. Ispan1, Sara Carillo2, Jonathan Bones2, Ken Cook3, Frank Steiner1, Mauro De Pra1 1Thermo Fisher Scientific, Germering, Germany 2…