sgRNA AND mRNA SEQUENCE MAPPING VIA ENDONUCLEASE DIGESTION AND LC-MS ANALYSIS, USING NOVEL INFORMATICS WORKFLOWS Catalin Doneanu1, Alexandre F. Gomes1, Chris Preston2, Matt Gorton2, Tatiana Johnson1, Bala Addepalli1, Heidi Gastall2 and Ying Qing Yu1 1Waters Corporation, Milford, MA, USA; 2Waters…
Key words
sgrna, digestion, uag, mse, mrna, sequence, mrt, mapping, nucleic, endonuclease, rapizyme, qtof, apps, xevo, mass