Sequence Mapping of mRNA Digests Using the Xevo™ MRT Mass Spectrometer and waters_connect™ MAP Sequence 2.0 Application

Application Note Sequence Mapping of sgRNA Digests: Leveraging Xevo™ MRT Mass Spectrometer Performance and Streamlining Data Analysis with MAP Sequence 2.0 Catalin Doneanu, Alexandre F Gomes, Tatiana Johnston, Chris Preston, Matt Gorton, Bala Addepalli, Scott Berger, Ying Qing Yu Waters…

MAP SEQUENCE - A NOVEL SOFTWARE APP FOR RAPID AND AUTOMATED SEQUENCE MAPPING OF mRNA MOLECULES Catalin Doneanu 1, Alexandre F Gomes 1 , Tatiana Johnston 1, Chris Preston 2, Matt Gorton 2, Bala Addepalli 1, 1 Christian Reidy 1,…

sgRNA AND mRNA SEQUENCE MAPPING VIA ENDONUCLEASE DIGESTION AND LC-MS ANALYSIS, USING NOVEL INFORMATICS WORKFLOWS Catalin Doneanu1, Alexandre F. Gomes1, Chris Preston2, Matt Gorton2, Tatiana Johnson1, Bala Addepalli1, Heidi Gastall2 and Ying Qing Yu1 1Waters Corporation, Milford, MA, USA; 2Waters…

SOFTWARE TOOLS FOR AUTOMATED LC/MS ANALYSIS OF CRITICAL QUALITY ATTRIBUTES OF mRNA MOLECULES Catalin Doneanu1, Alexandre F. Gomes1, Jo-Anne Riley2, Chris Preston2, Matt Gorton2, Tatiana Johnston1, Bala Addepalli1, and Ying Qing Yu1 1 Waters Corporation, Milford, MA, USA; 2Waters Corporation,…