Increased Identification Confidence for Extractables Screening Using the Xevo™ MRT Mass Spectrometer

The next frontier in extractables screening analyses: Increased identification confidence with a benchtop multi-reflecting time-of-flight mass spectrometer Rachel Sanig1, Lee A. Gethings1, Jayne Kirk1, Richard Lock1, Hernando Olivos2 Waters Corporation, UK1, Waters Corporation, US2 • • • • INTRODUCTION METHODS…

Application Note From Extractables Screening to Targeted Leachables Quantitation Using DDA and TofMRM on the Xevo™ MRT Mass Spectrometer Rachel Sanig, Jayne Kirk, Lee Gethings, Richard Lock Waters Corporation, United Kingdom Published on August 20, 2026 Abstract Due to the…

SCREENING FOR EXTRACTABLES AND LEACHABLES IN NASAL SPRAY DEVICES USING HIGH-RESOLUTION MASS SPECTROMETRY COMBINED WITH A DATA INDEPENDENT INFORMATICS STRATEGY Richard Lock1, Rachel Sanig1, Lee Gethings1, Jayne Kirk1, Sarah Dowd1, Nicholas Morley2 Waters Corporation, UK1, Element Materials Technology, UK2 INTRODUCTION…

Comprehensive extractables and leachables characterization through an integrated single injection Quan/Qual analysis using a benchtop multi-reflecting time-of-flight mass spectrometer Authors: Rachel Sanig1, Lee A. Gethings1, Jayne Kirk1, Richard Lock1, Shashank Jain2 Affiliations: 1Waters Corporation, UK 2Waters Corporation, US Introduction Experimental…