A Streamlined Workflow for the Characterisation and Relative Quantification of Recombinant Adeno-Associated Viruses using Charge Detection Mass Spectrometry

Application Note Streamlined Characterization of Recombinant AAVs via Charge Detection Mass Spectrometry: Insights from the USP AAV8 Reference Standards Rebecca J. D’Esposito, Anisha Haris, David Eatough, Vicki Knox, Ying Qing Yu, David Ballantyne, Stephen McDonald Waters Corporation, United States Published…

Customer note | 001049 Biotechnology Quantitative analysis of genome packaging in adeno-associated viruses using native MS Authors Key benefits Lisa Strasser1*, Tomos E. Morgan1, Felipe • Intact native mass spectrometry (MS) for the analysis of AAV-based viral vectors does not…

[ APPLICATION NOTE ] Anion-Exchange Chromatography for Determining Empty and Full Capsid Contents in Adeno-Associated Virus Hua Yang, Stephan Koza, and Weibin Chen Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■ ■ Empty and full AAV capsid separation Recombinant adeno-associated…

Characterizing Nucleic Acid Payloads in Lipid Nanoparticles and Viral Vectors via Charge Detection Mass Spectrometry (CDMS) Rebecca J. D'Esposito1; Alexandre Gomes1, Emily Christofi2; Ying Qing Yu1; Michelle Chen3 1Waters Corporation, Milford, MA; 2Waters Corporation, Wilmslow, United Kingdom; 3Waters Corporation, Goleta,…