Towards the Development of a Liquid Chromatography Free Workflow for Measurement of Clinically Important Proteins

Automated, High Precision Tryptic Digestion and SISCAPA-MS Quantification of Human Plasma Proteins Using the Agilent Bravo Automated Liquid Handling Platform Application Note Authors Abstract Morteza Razavi, N. Leigh Anderson, An “addition only” tryptic protein-digestion protocol, followed by multiplexed Matthew E.…

High Sensitivity SISCAPA-based Peptide Quantitation Using UHPLC and the 6490 QQQ with iFunnel Technology Application Note Clinical Research Authors Introduction Leigh Anderson SISCAPA Assay Technologies Rockville, MD USA Assays that are both specific and quantitative for target proteins and peptides…

Plasma proteomics goes high throughput – timsTOF Pro with PASEF and 4D feature alignment to quantify 500 plasma proteins in 11.5 min The timsTOF Pro with PASEF and the Evosep One for biomarker discovery in large sample cohorts of human…

Improving the Detection of Thyroglobulin in Human Plasma for Clinical Research by Combining SISCAPA Enrichment and Microflow LC-MS Jay S. Johnson,1 Morteza Razavi,2 James Murphy,1 Selena Larkin,2 and Paul Rainville1 1 Waters Corporation, Milford, MA, USA; 2 SISCAPA Assay Technologies,…