High-Resolution Size Exclusion Chromatography of Megadalton-Sized DNA Vectors and Plasmids Using Waters GTxResolve 2000 Å SEC Columns

Application Note Evaluating Volume Effects in SEC for Large Biomolecules on the Alliance™ iS Bio System With GTxResolve™ SEC 2000 Å Columns Abraham S. Finny, Balasubrahmanyam Addepalli Waters Corporation, United States Published on March 27, 2026 Abstract Analytical size-exclusion chromatography…

Application Note Slalom-Aided Anion Exchange Chromatography for Enhanced Analysis of Plasmid DNA Topological Impurities Abraham S. Finny, Fabrice Gritti, Szabolcs Fekete, Balasubrahmanyam Addepalli, Matthew A. Lauber Waters Corporation, United States Published on July 23, 2025 Abstract Slalom-Aided Anion Exchange Chromatography…

Application Note Enhancing Size-Exclusion Chromatography of Large Biomolecular Analytes With Rigorously Designed GTxResolve™ Premier SEC 1000 Å 3 µm Columns Abraham S. Finny, Lavelay Kizekai, Kristine Camacho, Oksana T'choul, Justin McLaughlin, Steven Byrd, MingCheng Xu, Balasubrahmanyam Addepalli, Matthew A. Lauber…

Application Note Using a 2.1 mm ID Narrow Bore GTxResolve™ Premier™ SEC Column to Reduce Sample Consumption During Size Exclusion Analyses Lavelay Kizekai, Balasubrahmanyam Addepalli, Matthew A. Lauber Waters Corporation This is an Application Brief and does not contain a…