ISOLATION OF A DEGRADATION PRODUCT OF RANITIDINE HYDROCHLORIDE USING THE WATERS ANALYTICAL SCALE PURIFICATION SYSTEM Authors: Margaret Maziarz, Ronan P. Cleary, Darcy Shave, Stephanie N. Harden, Paul D. Rainville, Jinxia Xia Affiliations: Waters Corporation, 34 Maple Street, Milford MA 01757…
Application Note Analytical Scale Isolation and Purification of Propranolol Impurities Including Nitrosamine Drug Substance Related Impurity (NDSRI) Margaret Maziarz, Paul Rainville, Stephanie Harden Waters Corporation, United States Published on Novemebr 07, 2025 Abstract Nitrosamine drug substance-related impurities (NDSRIs) are a…
Application Note Degradation Products of ARV-825 Proteolysis Targeting Chimera (PROTAC) Compound: Isolation and Purification Using Analytical Scale Fraction Collection Margaret Maziarz, Paul Rainville, Stephanie N Harden Waters Corporation, United States Published on July 10, 2025 Abstract Proteolysis targeting chimeras (PROTACs)…
Application Note Predictable Isolation of Radioligand Therapy Precursor PSMA-617 and Closely Eluting Impurities from a Forced Degradation Study Using a MaxPeak™ Premier OBD™ Preparative Column Jo-Ann Jablonski, Kathy Lawrence, Kenneth Berthelette Waters Corporation, United States Published on June 25, 2026…
