Using Targeted MRM MS Imaging With DESI to Visually Localize Isobaric And/or Low Abundance Lipids

Application Note High-Performance DESI-MSI using a DESI XS Xevo™ TQ Absolute XR system for Sensitive and Specific Targeted Imaging of Small Molecules in Tissue Sections Emmanuelle Claude Waters Corporation, Wilmslow, United Kingdom Published on September 23, 2025 Abstract Desorption Electrospray…

VISUALIZATION AND QUANTIFICATION OF DRUG/METABOLITES BY SENSITIVE AND FAST TARGETED DESI IMAGING ON TQ SYSTEM Emmanuelle Claude1, Ross Chawner1, Nathalie Delallée2, Stephanie Molez2, Gregory Nicolas2, Joanne Ballantyne1 1 Waters Corporation, Wilmslow, UK; 2Bioprojet, Saint Gregoire, France INTRODUCTION Mass spectrometry (MS)…

ADVANTAGES OF HIGH RESOLUTION ION MOBILITY ON THE CYCLIC IMS FOR DESI MASS SPECTROMETRY IMAGING 1 Susan Slade, 1Emmanuelle Claude. 1 Waters Corporation, Wilmslow, UK. INTRODUCTION RESULTS TM Desorption DESI is a powerful and sensitive MS ionisation technique for the…

[ APPLICATION NOTEBOOK ] MS IMAGING AND AMBIENT IONIZATION-MS FOR METABOLOMICS AND LIPIDOMICS 1 This notebook is an excerpt from the larger Waters’ Application Notebook on Metabolomics and Lipidomics #720005245EN TABLE OF CONTENTS 3 Introduction 4 Biomarker Discovery Directly from…