Comprehensive identification and label-free quantitation of host cell protein contaminants using BioPharma Finder 4.1 software

APPLICATION NOTE 74162 LC-MS-based host cell protein (HCP) identification and monitoring during biopharmaceutical downstream process development Authors: Xiaoxi Zhang1, Zijuan Chen2, Bingnan Li2, Jennifer Sutton3, Min Du4 Thermo Fisher Scientific 1 Shanghai, China; 2 Bioprocess Design Center, Shanghai, China; 3…

APPLICATION NOTE 21918 Easy, fast and reproducible analysis of host cell protein (HCP) in monoclonal antibody preparations Authors Giorgio Oliviero1, Ken Cook 2, Kai Scheffler3, Florian Füssl1, Jonathan Bones1 1National Institute for Bioprocessing Research and Training, Dublin, Ireland; 2Thermo Fisher…

APPLICATION NOTE 000242 Adeno-associated virus capsid protein characterization and host cell protein profiling using micro-flow UHPLC-Orbitrap MS Authors: Reiko Kiyonami1, Jennifer Sutton1, Katy Irvin2, Ken Cook3, Estee Toole4, Min Du5 Thermo Fisher Scientific, San Jose, CA; 2 Thermo Fisher Scientific,…

Biopharma Protein solutions eBook Protein therapeutics: At a glance Protein therapeutics are a type of biotherapeutics derived from genetically engineered human proteins. They offer several advantages over small-molecule drugs, allowing for more precise targeting of complex functions. Compared to chemical…