Efficient Profiling of Lipid Nanoparticle Formulations Using Waters GTxResolve 2000 Å SEC Column, MaxPeak Premier 3 μm

Application Note Deformulating Size Exclusion Chromatography for LNP Payload Quantitation Mateusz Imiolek, Szabolcs Fekete, Matthew A. Lauber Waters Corporation Abstract This application note discusses the use of a GTxResolve™ Premier BEH™ SEC 450 Å Column for the online deformulation of…

mRNA/LNP Multiattribute Quantitation of Payload(s), Size and Heterogeneity With Size Exclusion Chromatography Coupled to Multiangle Light Scattering a b b a Mateusz Imiołek , Lavelay Kizekai , Bala Addepalli , Szabolcs Fekete , Matthew Lauber a - Waters Corporation, Rue…

Application Note High-Throughput LNP Compositional Analysis Using GTxResolve™ RP 230 Å PH+ Columns: Method Development Considerations Mateusz Imiolek, Stephan M. Koza Waters Corporation, United States Published on June 08, 2026 Abstract This application note introduces a new GTxResolve Reversed Phase…

Application Note Biophysical Characterization of Enveloped VLPs Using a Waters GTxResolve™ 2000 Å SEC Column, MaxPeak™ Premier 3 µm Lavelay Kizekai, Balasubrahmanyam Addepalli, Sophia Kenrick, Matthew A. Lauber Waters Corporation, United States Published on December 19, 2025 Abstract Enveloped virus-like…