Platform Ion Pairing RPLC Method for Oligonucleotides Using High Throughput 20 mm Length Columns

Application Note Enhanced Resolution for Longer Oligonucleotide Analytes With a MaxPeak™ Premier Oligonucleotide BEH C18 300 Å Column Balasubrahmanyam Addepalli, Makda Araya, Matthew A. Lauber Waters Corporation Abstract Ion-pairing reversed phase liquid chromatography is widely used to characterize the identity,…

An Introduction to Ion-Paired Reverse-Phase Oligonucleotide Separations: From Analysis to Purification Melissa Goodlad, PhD Columns and Supplies Applications Engineer April 15, 2025 1 April 15, 2025 An Introduction to Ion-Paired Reverse-Phase Oligonucleotide Separations DE-006001 Introduction to Ion-Paired Reverse-Phase (IP-RP) Separations…

An Introduction to Ion-Paired Reverse-Phase Oligonucleotide Separations: From Analysis to Purification Melissa Goodlad, PhD Columns and Supplies Applications Engineer April 15, 2025 1 April 15, 2025 An Introduction to Ion-Paired Reverse-Phase Oligonucleotide Separations DE-006001 Introduction to Ion-Paired Reverse-Phase (IP-RP) Separations…

Application Note Reliable Purification of Full-Length Product and Enhanced Isolation and Detection of Impurities With Ready to Use XBridge Premier Oligonucleotide BEH™ C18 OBD™ Preparative Columns Michael Miller1, Paul Lefebvre1, Makda Araya2, Balasubrahmanyam Addepalli2, Mandana Fasth3, Christian Reidy2, Matthew Lauber2…