Enhanced SEC-MALS analysis of therapeutic mAbs, biosimilars and AAVs with XBridge Premier columns

Application Note Heightened Characterization of AAVs by SEC-MALS with XBridge™ Premier GTx BEH™ SEC 450 Å 2.5 µm Columns Lavelay Kizekai, Balasubrahmanyam Addepalli, Matthew A. Lauber Waters Corporation For in vitro diagnostic use. Not available in all countries. Abstract Gene…

Application Note Improved SizeExclusion Chromatography of Adeno-Associated Viruses (AAVs) With XBridge™ Premier GTx BEH™ SEC 450 Å 2.5 µm Columns Mateusz Imiolek, Szabolcs Fekete, Matthew A. Lauber Waters Corporation Abstract This application note discusses the use of XBridge™ Premier GTx…

CONSUMABLES GUIDE BOOK Characterizing AAVs Chromatographic methods to measure heterogeneity and critical quality attributes CONSUMABLES GUIDE BOOK A Changing Industry Attribute Testing The advent of FDA approved gene therapies brings An AAV vectored therapy contains multiple types of biomolecules compromised…

[ APPLICATION NOTEBOOK ] SIZE-EXCLUSION CHROMATOGRAPHY (SEC) OF PEPTIDES, PROTEINS, AND AAVs [ SIZE-EXCLUSION CHROMATOGRAPHY ] [ SIZE-EXCLUSION CHROMATOGRAPHY ] Introduction Gel-permeation chromatography (GPC), size-exclusion chromatography (SEC), and gel-filtration chromatography (GFC) are commonly used terms to describe a liquid chromatographic…