Improved Size- Exclusion Chromatography of Adeno-Associated Viruses (AAVs) With XBridge Premier GTx BEH SEC 450 Å 2.5 μm Columns

Application Note Heightened Characterization of AAVs by SEC-MALS with XBridge™ Premier GTx BEH™ SEC 450 Å 2.5 µm Columns Lavelay Kizekai, Balasubrahmanyam Addepalli, Matthew A. Lauber Waters Corporation For in vitro diagnostic use. Not available in all countries. Abstract Gene…

W H I T E PA P E R WP1618: Enhanced SEC-MALS analysis of therapeutic mAbs, biosimilars and AAVs with XBridge Premier columns Leo Liu, Ph.D., Waters | Wyatt Technology Summary SEC-MALS is widely used for the characterization of biopharmaceuticals.…

CONSUMABLES GUIDE BOOK Characterizing AAVs Chromatographic methods to measure heterogeneity and critical quality attributes CONSUMABLES GUIDE BOOK A Changing Industry Attribute Testing The advent of FDA approved gene therapies brings An AAV vectored therapy contains multiple types of biomolecules compromised…

[ APPLICATION NOTE ] Size-Exclusion Chromatography Analysis of Adeno-Associated Virus (AAV) Preparations Using a 450 Å Diol-Bonded BEH Column and Fluorescence Detection Stephan M. Koza and Weibin Chen Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■ ■ Optimization of SEC…