Quantifying quality attributes of AAV gene therapy vectors by SEC-UV-MALS-dRI

W H I T E PA P E R WP1618: Enhanced SEC-MALS analysis of therapeutic mAbs, biosimilars and AAVs with XBridge Premier columns Leo Liu, Ph.D., Waters | Wyatt Technology Summary SEC-MALS is widely used for the characterization of biopharmaceuticals.…

Next Steps in AAV Characterization via Light Scattering Measuring AAV Critical Quality Attributes Anatolii Purchel, Ph.D., Michelle Chen, Ph.D., John Champagne, Ph.D., Wyatt Technology Corporation SEC-MALS: Determines molar masses independently of elution time, and does not require calibration against reference…

Application Note Heightened Characterization of AAVs by SEC-MALS with XBridge™ Premier GTx BEH™ SEC 450 Å 2.5 µm Columns Lavelay Kizekai, Balasubrahmanyam Addepalli, Matthew A. Lauber Waters Corporation For in vitro diagnostic use. Not available in all countries. Abstract Gene…

Advances in Downstream PAT for Biologics, Vaccines and Gene Vectors Daniel Some – Waters | Wyatt Technology Contact: [email protected] How MALS works: scattered intensity vs. angle Abstract Multi-angle light scattering (MALS) is a versatile technology most commonly found in analytical…