Improved dia-PASEF isolation window schemes for proteomics measurements

Parallel accumulation – serial fragmentation combined with data-independent acquisition (diaPASEF) The timsTOF Pro with diaPASEF enables deeper proteome coverage in a single 4D shotgun proteomics experiment, with highly reproducible qualitative and quantitative results – making it a near-ideal mass analyzer…

AS MS 2 0 2 6 , TH P 3 6 4 Exploring the proteomics capabilities of a new Trapped Ion Mobility Q-TOF designed for enhanced metabolomics performances dia-PASEF; 100 ng k562; no MBR 9000 80000 Neat Isotopolog Plasma Peptides…

ASMS2025, TP202 Optimizing Selectivity and Ion Utilization for Trapped Ion Mobility Spectrometry for Enhanced DIA Performance Markus Lubeck1, Andreas Schmidt1, Stephanie Kaspar-Schoenefeld1, Matt Albano2, Cory Lytle2, Dijana Vitko2, Matthew Willetts2, Daniel Hornburg3 1Bruker Daltonics GmbH & Co. KG, Bremen, Germany,…

dia-PASEF® applied on different gradient lengths Data Independent Acquisition (DIA) workflows have gained in popularity as they overcome the issue of stochastic selection of peptide precursors encountered in typical data-dependent approaches (DDA) and thereby promise reproducible and accurate protein identification…