QUANTIFICATION OF THYROGLOBULIN IN SERUM FOR CLINICAL RESEARCH USING SISCAPA WORKFLOW COMBINED WITH LC-MS/MS

B-167 QUANTIFICATION OF THYROGLOBULIN IN SERUM FOR CLINICAL RESEARCH USING SISCAPA WORKFLOW COMBINED WITH LC-MS/MS Dominic Foley1, Morteza Razavi2, Robert Wardle1, Mary Trudeau1, Nadim Mira1 and Lisa J Calton1 1) Waters Corporation, Wilmslow, Cheshire, UK. 2) SISCAPA Assay Technologies, Washington…

Improving the Detection of Thyroglobulin in Human Plasma for Clinical Research by Combining SISCAPA Enrichment and Microflow LC-MS Jay S. Johnson,1 Morteza Razavi,2 James Murphy,1 Selena Larkin,2 and Paul Rainville1 1 Waters Corporation, Milford, MA, USA; 2 SISCAPA Assay Technologies,…

LC-MS/MS ANALYSIS OF MABS USING A MONOCLONAL ANTIBODIES QUANTIFICATION KIT – SPOTLIGHT ON INFLIXIMAB Dominic Foley1, John Vukovic1, Dorothée Lebert2, Lisa J Calton1 1. Waters Corporation, Wilmslow, Cheshire, UK 2. Promise Proteomics, Grenoble, France INTRODUCTION Therapeutic monoclonal antibodies (t-mAbs) have…

B-155 LC-MS/MS ANALYSIS OF MABS USING A MONOCLONAL ANTIBODIES QUANTIFICATION KIT – SPOTLIGHT ON INFLIXIMAB Dominic Foley1, John Vukovic1, Dorothée Lebert2, Lisa J Calton1 1. Waters Corporation, Wilmslow, Cheshire, UK 2. Promise Proteomics, Grenoble, France INTRODUCTION Therapeutic monoclonal antibodies (t-mAbs)…