LC-MS/MS ANALYSIS OF MABS USING A MONOCLONAL ANTIBODIES QUANTIFICATION KIT – SPOTLIGHT ON INFLIXIMAB

B-155 LC-MS/MS ANALYSIS OF MABS USING A MONOCLONAL ANTIBODIES QUANTIFICATION KIT – SPOTLIGHT ON INFLIXIMAB Dominic Foley1, John Vukovic1, Dorothée Lebert2, Lisa J Calton1 1. Waters Corporation, Wilmslow, Cheshire, UK 2. Promise Proteomics, Grenoble, France INTRODUCTION Therapeutic monoclonal antibodies (t-mAbs)…

Application Note mAbs Testing in Inflammation Using Mass Spectrometry – Combination of mAbXmise™ Kits and XEVO™ TQ Absolute XR Mass Spectrometer Davor Fielitza, Dorothée Lebertb a Waters Corporation, Eschborn, Germany b Promise Proteomics, Grenoble, France Published on February 18, 2026…

[ APPLICATION NOTE ] Development of a Hybrid Immunoaffinity-LC-MS/MS Method for the Quantification of Active Biotherapeutics Targeting TNF-α in Serum Caitlin Dunning and Mary Lame Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ High analytical sensitivity Tumor Necrosis Factor…

[ APPLICATION NOTEBOOK ] PEPTIDE AND PROTEIN BIOANALYSIS [ OUR SCIENTISTS ] Yun Alelyunas, PhD Before coming to Waters in 2012, Yun Alelyunas was a principal scientist and team leader at AstraZeneca for 20 years where she was involved in…