Quantifying Oligonucleotides (CONSUMABLES GUIDE BOOK)

M0930-06-36 ELEMENTS OF ROBUST MODIFIED OLIGONUCLEOTIDE EXTRACTION THROUGH SPE Makda Araya, Abraham Finny, Balasubrahmanyam Addepalli and Matthew Lauber Waters Corporation CONTACT INFORMATION: [email protected] PURPOSE RESULTS Extraction and Quantification of Therapeutic Oligonucleotides (OTx) during Bioanalysis Robust extraction of modified and unmodified…

ELEMENTS OF ROBUST MODIFIED OLIGONUCLEOTIDE EXTRACTION THROUGH SPE Makda Araya, Abraham Finny, Balasubrahmanyam Addepalli, Mandana Fasth and Matthew Lauber Waters Corporation INTRODUCTION RESULTS AND DISCUSSION Extraction and Quantification of Therapeutic Oligonucleotides (OTx) during Bioanalysis Robust extraction of modified and unmodified…

Application Note Improved Bioanalytical Extraction of Therapeutic Antisense Oligonucleotides, Including a Lipid Conjugated ASO From Liver and Brain Tissue Using the OligoWorks™ SPE Microplate Kit Makda Araya, Mary Trudeau, Balasubrahmanyam Addepalli, Matthew A. Lauber Waters Corporation Abstract To develop and…

Application Note Improved Recovery of a Lipid Conjugated Antisense Oligonucleotide from Human Plasma using the OligoWorks™ SPE Microplate Kit and an Optimized Protocol Mary Trudeau, Matthew A. Lauber Waters Corporation This is an Application Brief and does not contain a…