LC Method Adjustment Made Simple: A Practical Guide

[ APPLICATION NOTE ] Scaling of a USP Assay for Quetiapine Fumarate Across Different Liquid Chromatographic Systems Amanda B. Dlugasch, Jennifer Simeone, and Patricia R. McConville Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ The Waters Column Calculator enables…

Major changes and extensions in the pharmacopoeias Rainer Turek Regional Business Development, EMEA Outline United States Pharmacopoeia, USP–NF 2022, Issue 3 Chapter 621: Chromatography (Official Date Dec. 1, 2022)  Unites States Pharmacopoeia – Changes in <621> Chromatography – <1220>…

MODERNIZATION OF AN ANTIVIRAL IMPURITIES MONOGRAPH USING THE GLOBALLY HARMONIZED PHARMACOPEIAL GUIDANCE FOR LIQUID CHROMATOGRAPHY Catharine E. Layton, Paul D. Rainville, Michael Baynham Waters Corporation, 34 Maple St., Milford, MA, USA INTRODUCTION The U.S. Pharmacopeia USP portfolio of solutions addresses…

[ APPLICATION NOTE ] Gradient Method Scaling for Life Cycle Management of a USP Impurities Method Amanda B. Dlugasch, Jennifer Simeone, and Patricia R. McConville Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ The Waters™ Columns Calculator enables Pharmaceutical…