High Resolution Peptide Mapping for Biopharmaceutical Analysis

Carsten Paul and Mauro De Pra Thermo Fisher Scientific, Germering, Germany Key Words Acclaim C18 RSLC, Biocompatible UHPLC, Biopharma, Biotherapeutics Characterization, Monoclonal Antibodies, Protein Digest, Vanquish UHPLC System Goal Evaluate the long-term stability of peptide mapping on a Vanquish UHPLC…

Carsten Paul and Mauro De Pra Thermo Fisher Scientific, Germering, Germany Key Words Acclaim C18 RSLC, Biocompatible UHPLC, Biopharma, Biotherapeutics Characterization, Monoclonal Antibodies, Protein Digest, Vanquish UHPLC System Goal Evaluate the long-term stability of peptide mapping on a Vanquish UHPLC…

Valeria Barattini, Joanna Freeke, Thermo Fisher Scientific, Runcorn, Cheshire, UK Key Words Accucore C18, bottom-up proteomics, proteins, peptides, fused core, superficially porous, 150 Å, bovine serum albumin (BSA) Abstract This application note demonstrates the analysis of trypsin-digested BSA using a…

Application note | 001123 Biopharma Consistent results for peptide mapping and monitoring across three systems of the Vanquish UHPLC platform Authors Goal Craig Jakes1,2, Silvia Millán-Martín1, Assessing consistency, reproducibility of results, and method transferability across Sara Carillo , Dennis Köhler…