Consistent results for peptide mapping and monitoring across three systems of the Vanquish UHPLC platform

APPLICATION NOTE 000336 An integrated LC-MS system performance evaluation test for peptide mapping and monitoring Authors: Hao Yang1, Melissa Sato1, Royston Quintyn2, Catharina Crone3, Julia Kraegenbring3 Kai Scheffler4, Min Du5, Thermo Fisher Scientific, San Jose, CA, US 1 2 Thermo…

Table of Contents Introduction Faster and More Sensitive Protein Characterization and Quantitation Easier Digestion Faster Digestion Highly Reproducible Digestion Automation of Digestion Improving Sensitivity and Speed SMART Digest Peptide Mapping and Quantitation Compendium Peptide Mapping Peptide Quantitation Product and Method…

Demonstrate Method Robustness and Seamless Method Transfer, a Step Towards Enabling High Resolution Accurate Mass Multi-Attribute Method for Biotherapeutic QC Hao Yang1; Melissa N. Sato1; Royston Quintyn2; Kai Scheffler3; Catharina Crone3; Julia Kraegenbring3; Alexander Harder3; Artem Akhmetov4; Jennifer Sutton4 1Thermo…

TECHNICAL NOTE 72203 Tandem UHPLC operation for high-throughput LC-MS peptide mapping analyses Authors Martin Samonig, Sabrina Patzelt, Carsten Paul, Martin Rühl, and Remco Swart Thermo Fisher Scientific, Germering, Germany Keywords Dual column, dual gradient, offline reconditioning, alternating column regeneration, Vanquish…