Resolve Uncertainty and Speed Through AAV Aggregate Analysis with Platform Methods

Application Note Improved SizeExclusion Chromatography of Adeno-Associated Viruses (AAVs) With XBridge™ Premier GTx BEH™ SEC 450 Å 2.5 µm Columns Mateusz Imiolek, Szabolcs Fekete, Matthew A. Lauber Waters Corporation Abstract This application note discusses the use of XBridge™ Premier GTx…

[ APPLICATION NOTE ] Size-Exclusion Chromatography Analysis of Adeno-Associated Virus (AAV) Preparations Using a 450 Å Diol-Bonded BEH Column and Fluorescence Detection Stephan M. Koza and Weibin Chen Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■ ■ Optimization of SEC…

[ APPLICATION NOTEBOOK ] SIZE-EXCLUSION CHROMATOGRAPHY (SEC) OF PEPTIDES, PROTEINS, AND AAVs [ SIZE-EXCLUSION CHROMATOGRAPHY ] [ SIZE-EXCLUSION CHROMATOGRAPHY ] Introduction Gel-permeation chromatography (GPC), size-exclusion chromatography (SEC), and gel-filtration chromatography (GFC) are commonly used terms to describe a liquid chromatographic…

by Phenomenex Biopharmaceutical Chromatography Solutions Novel Particles 10 Chemistries Peptide Mapping (RP) Peptide Quantitation (RP) Aggregate Analysis (SEC) Charge Variant Analysis (IEX) Glycan Analysis (HILIC) Intact and Fragment Analysis (RP) Intact Mass (RP) Drug Antibody Ratio (RP) Oligonucleotide Analysis (RP)…