Polymer Studio: a novel software for fast profiling and identifying complex pharmaceutic excipients by UHPLC- HRMS/MSn technique

APPLICATION NOTE 73979 Polysorbate 80 profiling by HPLC with mass and charged aerosol detection Authors: Mauro De Pra, Denis A. Ispan, Katherine Lovejoy, Sylvia Grosse, Stephan Meding, Frank Steiner Thermo Fisher Scientific, Germering, Germany Keywords: Vanquish Flex, Vanquish Duo, ISQ…

Table of contents Summary Overview Excipient function Measurement Charged Aerosol Detector Universal detection Uniform response Working principles (U)HPLC Systems with CAD Columns choice Excipients overview Adjuvants Amino acids Carbohydrates Counterions Nonionic surfactants Polyethylene glycol Proteins and excipients HPLC-Charged Aerosol Detection…

Poster Reprint ASMS 2025 Poster number ThP 752 Comprehensive Investigation of Polymer Oxidation using Interactive Visualizations and User Modified Libraries in PolyMatch Suite Wendi A Hale1; Jeremy P Koelmel2; Nicholas Oranzi3; David Weil4; Emma E. Rennie4; Paul Stelben2; Michael Kummer5;…

Simultaneous analysis of polysorbate 80 and poloxamer 188 in biopharmaceutical formulations using charged aerosol detector and single quadrupole mass spectrometer Xuepu Li 1, Sissi White 2, Mauro De Pra 3, Yu Cui 1, Min Du 2 1Thermo Fisher Scientific, Shanghai,…