STABILITY CHARACTERIZATION OF MULTIPLE SEROTYPES OF ADENO-ASSOCIATED VIRUS USING CHARGE DETECTION MASS SPECTROMETRY

Determination of Full, Partial and Empty Capsid Ratios for Adeno-Associated Virus (AAV) Analysis Tingting Li, Tie Gao, Hongxu Chen, Zuzana Demianova, Fang Wang, Mukesh Malik, Jane Luo, Handy Yowanto, Sahana Mollah SCIEX, Brea, CA Introduction Adeno-associated virus (AAV) is one…

[ APPLICATION NOTE ] Anion-Exchange Chromatography for Determining Empty and Full Capsid Contents in Adeno-Associated Virus Hua Yang, Stephan Koza, and Weibin Chen Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■ ■ Empty and full AAV capsid separation Recombinant adeno-associated…

Comprehensive AAV Characterizations Using HRMS: Peptide Mapping, Capsid Proteins, Intact ssDNA, and Intact Virus T1430-09-53 Hua Yang, Ying Qing Yu, Stephan Koza, Suraj Dhungana, Ann Gray Waters Corporation, 34 Maple Street, Milford, Massachusetts, USA CONTACT INFORMATION: [email protected] PURPOSE RESULT(S) CONCLUSION(S)…

Customer note | 001049 Biotechnology Quantitative analysis of genome packaging in adeno-associated viruses using native MS Authors Key benefits Lisa Strasser1*, Tomos E. Morgan1, Felipe • Intact native mass spectrometry (MS) for the analysis of AAV-based viral vectors does not…