Multi-attribute monitoring of aggregates and charge variants of monoclonal antibody through native 2D- SEC-MS-WCX-MS

Poster Reprint ASMS 2023 Poster number MP 630 Rapid analysis of titer, aggregate and intact mass of antibody therapeutics using multi-dimensional liquid chromatography coupled with native mass spectroscopy Tushar Sharad Savane1, Sunil Kumar1, Vadiraja Bhat2, Anurag Singh Rathore1 1 Department…

Poster Reprint ASMS 2022 Poster number ThP407 Multi-Attribute Monitoring of Antibody Variants through Hydrophobic and CationExchange Chromatography Coupled with Native Mass Spectrometry Sunil Kumar1, Deepika Sarin1, Vadiraja Bhat2, David L. Wong3, Anurag Singh Rathore1 Department of Chemical Engineering, Indian Institute…

2D-LC/MS Characterization of Charge Variants Using Ion Exchange and Reversed-Phase Chromatography Multiple Heart-Cutting 2D-LC Analysis of Innovator versus Biosimilar Monoclonal Antibodies Application Note Biotherapeutics and Biologics Author Abstract Sonja Schneider The determination of charge variants is one of the most…

Poster Reprint ASMS 2023 Poster number MP 625 A native multi-dimensional monitoring workflow for at-line characterization of mAb titer, size, charge, and glycoform heterogeneities in cell culture supernatant Sanghati Bhattacharya1, Shashank Jain2 , Vadiraja Bhat3, Srishti Joshi1, Anurag S. Rathore1…