A Simple and Reliable Technique for Trace Level Quantification of Nitrite as Precursors of N- nitrosation in pharmaceutical samples

Application Note Enhancing Efficiency: Fast and Reliable Nitrite Content Analysis in Pharmaceutical Excipients With the ACQUITY™ QDa™ II Mass Detector Henry Foddy, Amy Bartlett, Victoria Starkie, Jonathan Pugh, Cristian Cojocariu Waters Corporation Abstract Benefits ■ Demonstrate the robust capabilities of…

Application Note A Sensitive and Cost-Effective LC–MS Method for Quantifying N-Nitroso-Atenolol in Drug Formulation Henry Foddya, Matthew Gregoryb, Joe Lackeyb, Moritz Perscheidb, Neil Walsha a Waters Corporation, Wilmslow, United Kingdom b LGC Standards, Guildford, United Kingdom Published on December 09,…

ACQUITY QDa II Mass Detector Advancing the Power of Mass Detection Elevate Your Analytical Insights and Press On for Even More Identify Everything in Your Sample with Complete Confidence Information-rich mass spectral data starts here Built on a solid foundation…

Pharma and biopharma Nitrosamine impurities analysis solutions guide • Find the right analytical solution for each stage of nitrosamine impurity analysis • Confidently detect and quantify genotoxic impurities in active pharmaceutical ingredients and finished drug products Contents Advancing confidence in…