CONSIDERATIONS FOR METHOD MIGRATION BETWEEN HPLC PLATFORMS IN THE ANALYTICAL LABORATORY

[ WHITE PAPER ] Dwell Volume and Extra-Column Volume: What Are They and How Do They Impact Method Transfer? Paula Hong and Patricia R. McConville Waters Corporation, Milford, MA, USA A chromatographic separation is impacted by numerous factors, including the…

Application Note Scaling and Migration of a Hydrophilic Interaction Liquid Chromatography (HILIC) Method for Related Compounds of Ribavirin to Modern HPLC Systems Margaret Maziarz Waters Corporation Abstract Achieving identical chromatographic separation and equivalent results are critical for a successful method…

IMPACT OF INSTRUMENT CHARACTERISTICS ON THE METHOD MIGRATION OF A CHALLENGING USP ASSAY Anthony Dovell, Paula Hong Waters Corporation, Milford, MA 01757 INTRODUCTION USP monographs are designed to provide the user with the information needed to execute a given test.…

Scaling Reverse-Phase and Hydrophilic Interaction Liquid Chromatography (HILIC) Methods to HPLC Authors: Margaret Maziarz, Paul Rainville, Stephanie Harden Affiliations: Waters Corporation, 34 Maple Street, Milford MA 01757 2.0 mL/min Step Time %A 1 Initial 90.0 %B 5.0 %C Curve 5.0…