System preparation for optimized oligonucleotide analysis

Application note | 001108 Biopharma Characterization of mRNA 5’ capping products using an LC-HRAM-MS/MS analytical platform and Thermo Scientific BioPharma Finder software solution Authors Goal Robert L Ross, Keeley Murphy, Yi Zhang, To develop a sensitive and robust LC-HRAM-MS/MS method…

Application note | 001183 Biopharma Characterization of in vitro-transcribed (IVT) mRNA poly(A) tail by LC-HRAM-MS and BioPharma Finder 5.0 software Authors Application benefits Robert L. Ross1, Jenny England2, Rhonda • Confident identification and sequence confirmation of polyadenylated tails in synthetic…

Application note | 002601 Biopharma Confident intact mass analysis of the tRNA isodecoders of phenylalanine by UHPLC-HRAM-MS and BioPharma Finder software Application benefits Authors Robert L. Ross1, Keeley Murphy1, • Confident and sensitive identification of biological transfer ribonucleic acid (tRNA)…

Oligonucleotide sequencing by LC-MS/MS: A novel Approach for Characterization and Quality Control of mRNA-based Vaccines and Biotherapeutics Alexander Schwahn, Angela Criscuolo, and Ken Cook The world leader in serving science 1 [email protected] | ISC2022 Why have oligonucleotides become so popular?…