High-precision, automated peptide mapping of proteins

APPLICATION NOTE 21834 Automated chymotrypsin peptide mapping of proteins by LC-MS Authors Amy Farrell1, Jonathan Bones1, Ken Cook 2 1 Characterisation and Comparability Laboratory, NIBRT – The National Institute for Bioprocessing Research and Training, Dublin, Ireland 2 Thermo Fisher Scientific,…

Table of Contents Introduction Faster and More Sensitive Protein Characterization and Quantitation Easier Digestion Faster Digestion Highly Reproducible Digestion Automation of Digestion Improving Sensitivity and Speed SMART Digest Peptide Mapping and Quantitation Compendium Peptide Mapping Peptide Quantitation Product and Method…

Protein digestion for peptide mapping and quantitation Overview of SMART Digest and SMART Digest ImmunoAffinity Kits SMART Digest and SMART Digest ImmunoAffinity kits Thermo Scientific™ SMART Digest™ and the SMART Digest™ ImmunoAffinity (IA) kits are designed for biomarker and bio-therapeutic…

APPLICATION NOTE 21782 Comparison of alternative approaches to trypsin protein digestion for reproducible and efficient peptide mapping analysis of monoclonal antibodies Authors Silvia Millán-Martín, Craig Jakes, Noemi Dorival-García, Nicola McGillicuddy, Sara Carillo, Amy Farrell, Jonathan Bones National Institute for Bioprocessing…