Simplify your mRNA purification process

Application note | 000471 Liquid chromatography Simultaneous reversed-phase and anion-exchange method scouting with a dual system for mRNA impurity determination Authors Application benefits Denis Andrei Ispan, Mauro De Pra, • Leverage two different separation chemistries in the same instrument at…

Application note | 001183 Biopharma Characterization of in vitro-transcribed (IVT) mRNA poly(A) tail by LC-HRAM-MS and BioPharma Finder 5.0 software Authors Application benefits Robert L. Ross1, Jenny England2, Rhonda • Confident identification and sequence confirmation of polyadenylated tails in synthetic…

A simple and robust LC-MS method for determination of poly(A) tail length using the Orbitrap Exploris MS systems Hao Yang, Robert Ross, Keeley Murphy, Yi Zhang, Min Du, Thermo Fisher Scientific, San Jose, CA, USA INTRODUCTION The introduction of effective…

Application brief | 003060 Biopharma Accurate and consistent analysis of poly(A) tails of mRNA therapeutics on a UHPLC-HRAM-MS platform Application benefits Authors Hao Yang , Robert Ross , Min Du • Accurate and consistent measurement of poly(A) tail length and…