Automating Rapid High-throughput mAb Attribute Screening of Microbioreactor Cell Culture Media Samples

Application Note Automating Rapid High-Throughput LC-MS mAb Subunit Screening of Microbioreactor Cell Culture Samples Alireza Aghayee, Yamin Htet, Stephan M. Koza, Lindsay Morrison, Henry Shion, Ying Qing Yu Waters Corporation Abstract Monoclonal antibodies (mAbs) remain one of the fast-growing classes…

[APPLICATION NOTEBOOK] At-line Solutions for Upstream Bioprocessing Application Notes [APPLICATION NOTEBOOK] Introduction Bioprocessing harnesses the power of living cells to manufacture valuable products such as biological drugs for clinical use. The introduction and use of biologics has revolutionized biotherapeutics to…

[ APPLICATION NOTEBOOK ] Multi-Attribute Methods for Biopharmaceutical Analysis Application Notes [ APPLICATION NOTEBOOK ] Introduction The adoption of LC-MS-based multi-attribute method (MAM) analysis for routine monitoring of biotherapeutic variation has progressed greatly over the last five years. The ability…

Application Note Rapid Automated Antibody Purification Using Protein A-Coupled Magnetic Beads With Andrew+ Yamin Htet, Stephan M. Koza, Weibin Chen Waters Corporation For research use only. Not for use in diagnostic procedures. Abstract Monoclonal antibodies remain one of the rapid…