Tandem UHPLC operation for high-throughput LC-MS peptide mapping analyses

TECHNICAL NOTE 72203 Tandem UHPLC operation for high-throughput LC-MS peptide mapping analyses Authors Martin Samonig, Sabrina Patzelt, Carsten Paul, Martin Rühl, and Remco Swart Thermo Fisher Scientific, Germering, Germany Keywords Dual column, dual gradient, offline reconditioning, alternating column regeneration, Vanquish…

TECHNICAL NOTE Authors: Martin Samonig, Sabrina Patzelt, Martin Rühl, and Remco Swart Thermo Fisher Scientific, Germering, Germany Key words Pre-concentration, trap and elute, desalt, MSPac, MAbPac, monoclonal antibody, mAb, Vanquish, reversed phase, mass spectrometry, Q Exactive, biopharmaceutical, biomolecules, intact protein…

Technical note | 001259 Native mass spectrometry Rapid online buffer exchange Solutions for high-throughput analysis of large biomolecules by native mass spectrometry Authors Why do we need rapid online buffer exchange? Weijing Liu , Samy Memmi , Terry Zhang ,…

TECHNICAL NOTE 73298 Flexible HPLC instrument setups for double usage as one heart-cut-2D-LC system or two independent 1D-LC systems Authors: Maria Grübner and Giorgia Greco Thermo Fisher Scientific, Germering, Germany Keywords: Two-dimensional liquid chromatography, 2D-LC, 2D-HPLC, heart-cut-2D-LC, Vanquish Duo UHPLC…