HILIC – an alternative separation technique for glycopeptides

APPLICATION NOTE 72604 Comparison of therapeutic antibody originator and biosimilar glycosylation using an integrated glycan labeling solution Authors Alexander Ley and Mauro De Pra Thermo Fisher Scientific, Germering, Germany Goal Demonstrate the suitability of the Applied Biosystems™ GlycanAssure™ HyPerformance APTS…

Thermo Scientific Vanquish Flex UHPLC System Built for Biopharma Characterization of biotherapeutics including: Proteins Monoclonal antibodies Antibody drug conjugates Engineered to build your DRUG PIPELINE The world of biotherapeutic characterization is undergoing a revolution. Development of evermore complex protein-based therapeutics…

Biopharmaceutical Characterisation Compendium A complete toolbox of techniques, workflows and technologies for comprehensive biopharmaceutical characterisation Please click the circles to navigate INTRODUCTION AGGREGATE ANALYSIS CHARGE VARIANT ANALYSIS PEPTIDE MAPPING GLYCANS INTACT AND SUBUNIT ANALYSIS INTRODUCTION The resources collected in this…

Technical note | 003308 Pharma / Biopharma Compliance-ready LC-UV-MS-based monitoring of antibody quality attributes using a single quadrupole mass spectrometer Authors Application benefits Sylvia Grosse1, Michaela S. Scherz1, • The Thermo Scientific™ ISQ™ EM Single Quadrupole Mass Spectrometer (SQMS) enables…