Simultaneous Separation and Quantification of Aminoglycosides Using Liquid Chromatography and Mass Spectrometry

Application Note An Ultra Performance Liquid Chromatography Mass Spectrometry Method for the Analysis of Non-derivatized Gentamicin Components Adam Bengtson, Fadi L. Alkhateeb, Paul D. Rainville Waters Corporation Abstract Gentamicin, an aminoglycoside that lacks chromophores, is commonly used as a broad-spectrum…

Application Note Analysis of Aminoglycosides in Foods Using a Zwitterionic Stationary Phase and Liquid Chromatography-Tandem Mass Spectrometry Jinchuan Yang, Paul D. Rainville Waters Corporation Abstract The effects of chromatographic conditions, such as mobile phases, pH, and ionic strength (or buffer…

Application Note Analysis of Free Inositol Stereoisomers in Dietary Supplements by Hydrophilic Liquid Chromatography using the Arc™ Premier System and ACQUITY™ QDa™ II Mass Detector Jinchuan Yang, Stephanie Harden, Paul Rainville Waters Corporation, United States Published on December 24, 2025…

Application Note Analysis of Creatine and Creatinine in Dietary Supplements Using HILIC-MS Kenneth Berthelette, Euan Ross, Thomas H Walter Waters Corporation, United States Published on August 14, 2026 Abstract A hydrophilic interaction liquid chromatography-mass spectrometry (HILIC-MS) method was developed to…